Exploring the ameliorative role of α7 neuronal nicotinic acetylcholine receptor modulation in epilepsy and associated comorbidities in post-PTZ-kindled mice.

•Postkindled animals showed significant comorbid depression and memory deficit.•Behavioral and biochemical parameters were used to assess epilepsy and associated comorbidities.•Altered neurochemistry was estimated in cortex and hippocampus of animals.•Choline chloride showed ameliorative effect in epilepsy and associated comorbidities.