Assessment of clinical performance of an ultrasensitive nanowire assay for detecting human papillomavirus DNA in urine.

HyungJae Lee,Mihye Choi,Minkyung Jo,Eun Young Park,Sang-Hyun Hwang,Youngnam Cho

Gynecologic Oncology（2020）

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摘要

•Nanowire assay can detect HPV DNA in urine with high sensitivity and specificity.•Non-invasive, urine-based HPV screening can increase cervical cancer effectiveness.•HPV type-specific concordance rate between urine and cervical samples was over 90%.

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cfDNA,HPV,PEI-NWs,hrHPV,LBC,NW,HPR,HRP-st NPs,TMB,ROC curve,AUC,PPV,NPV

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