Ubiquitin Ligase LRSAM1 Suppresses Neurodegenerative Diseases Linked Aberrant Proteins Induced Cell Death.

Ribhav Mishra,Ayeman Amanullah,Arun Upadhyay,Rohan Dhiman,Ankur Rakesh Dubey,Sarika Singh,Amit Prasad,Amit Mishra

The International Journal of Biochemistry & Cell Biology（2020）

引用 8|浏览27

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摘要

•LRSAM1 can function as a quality control E3 Ubiquitin Ligase.•Recruitment of LRSAM1 towards misfolded proteins.•LRSAM1 levels induced under various stress conditions.•Cytoprotective nature of LRSAM1 alleviates proteotoxic insults.

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ALS,CHIP,CMT2P,DMSO,E6-AP,ER,H2O2,HRP,HS,IB,ITCH,MGRN1,MTOC,MTT,PBS,PQC,QC,TBST,TSG101,TUNNEL,UPS

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