Ubiquitin Ligase LRSAM1 Suppresses Neurodegenerative Diseases Linked Aberrant Proteins Induced Cell Death
The international journal of biochemistry & cell biology, pp. 1056972020.
Cell DeathHsp70LRSAM1Misfolded ProteinsUbiquitin Ligase
Accumulation of aberrant misfolded proteins is a major hallmark of several neurodegenerative diseases. Intracellular accumulations of such abnormal proteins are selectively cleared by the ubiquitin-proteasome system (UPS). But how the failure of misfolded protein degradation cause proteinopathies is still an unanswered question?. Previous...More
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