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Ubiquitin Ligase LRSAM1 Suppresses Neurodegenerative Diseases Linked Aberrant Proteins Induced Cell Death.

The International Journal of Biochemistry & Cell Biology, (2020): 105697

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Abstract

•LRSAM1 can function as a quality control E3 Ubiquitin Ligase.•Recruitment of LRSAM1 towards misfolded proteins.•LRSAM1 levels induced under various stress conditions.•Cytoprotective nature of LRSAM1 alleviates proteotoxic insults.

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Author
Ribhav Mishra
Ribhav Mishra
Rohan Dhiman
Rohan Dhiman
Ankur Rakesh Dubey
Ankur Rakesh Dubey
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