Quantification of Phospholipid Degradation Products in Liposomal Pharmaceutical formulations by Ultra Performance Liquid Chromatography-Mass Spectrometry (UPLC-MS).

•Development of an UPLC-QTOF based method for the quantitation of phospholipids degradation products.•Analysis of lipid degradation products including free fatty acids, lysophosphatidylcholines and lysophosphatidylglycerol.•Baseline separation of enantiomeric forms of sn-1 and sn-2 lysophospholipids on C18 column.