Method matters: Development of characterization techniques for branched and glucose-poly(lactide-co-glycolide) polymers

Justin Hadar
Justin Hadar
Sarah Skidmore
Sarah Skidmore
John Garner
John Garner
Haesun Park
Haesun Park
Bin Qin
Bin Qin
Xiaohui Jiang
Xiaohui Jiang
Darby Kozak
Darby Kozak

Journal of Controlled Release, pp. 484-494, 2020.

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Abstract:

Defining the qualitative sameness of parenteral formulations comprised of poly(lactide-co-glycolide) (PLGA) requires assays of the relevant properties of polymer from each formulation. Gel-permeation chromatography with quaternary detection (GPC-4D) has been previously applied to other polymers, and the relevant mathematical parameters fo...More

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