Descriptive Analysis of Everolimus Conversion in Liver Transplant Recipients With Malignant Neoplastic Disease.

Transplantation Proceedings(2020)

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摘要
•After liver transplant because of hepatocellular carcinoma, patients who do not meet Milan criteria and have vascular microinvasion in the explant have a lower survival.•Malignant neoplasms after solid organ transplant are substantially more frequent than in the general population and remain a major cause of post-transplant mortality.•One of the best-documented associations between immunosuppression and risk of malignant neoplasms is for the calcineurin inhibitor class of drugs.•Everolimus appears to offer a potential option for reducing the risk for hepatocellular carcinoma recurrence after liver transplant and better survival with de novo tumors.
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