Polyoxovanadate-iodobodipy supramolecular assemblies: new agents for high efficiency cancer photochemotherapy.
CHEMICAL COMMUNICATIONS(2020)
摘要
Two novel polyoxovanadate-iodoBodipy supramolecular assemblies, named as (2I-BDP-C-6)(2)V-6 and (2I-BDP-C-6)(3)V-10, were first synthesized by the self-assembly of anionic hexavanadate and decavanadate with cationic iodoBodipy for photochemotherapy, respectively. The mechanisms for synergistic photochemotherapy of the anion-cation pairs were determined. In particular, (2I-BDP-C-6)(3)V-10 can effectively kill lung cancer cells (HepG2) by synergetic chemotherapy as well as photodynamic therapy.
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