Locally delivered minocycline microspheres do not impair osseointegration of titanium implants in a rat femur model.

Joshua A Shapiro, Samuel AbuMoussa,Christopher P Lindsay, Gabriel B Mason,Laurence E Dahners,Paul S Weinhold

Journal of Orthopaedics（2020）

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摘要

Peri-implant minocycline administration did not impair implant fixation strength or peri-implant bone-volume, supporting its potential utility as an adjunct to intramedullary implants.

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关键词

Minocycline,Osseointegration,Pushout testing,Bone volume fraction,Sprague-Dawley

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