Changing therapeutic strategies and persistence to disease-modifying treatments in a population of multiple sclerosis patients from Veneto region, Italy.

Antonio Marangi,Gabriele Farina, Virginia Vicenzi,Stefano Forlivesi,Francesca Calabria,Fabio Marchioretto, Antonio Forgione,Francesca Rossi,Gianola Stenta,Marika Vianello,Alberto Gajofatto,Maria Donata Benedetti

Multiple Sclerosis and Related Disorders（2020）

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摘要

•Dimethylfumarate and fingolimod represent the most prescribed DMTs.•54,8% of patients stopped their treatment within the last follow-up.•Dimethylfumarate use predicted higher persistence at 24 months.•Glatiramer acetate and azathioprine had the highest persistence at last follow-up.•Longer disease duration was predictive of an increased risk of DMT discontinuation.

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关键词

Observational studies,Epidemiology,Multiple sclerosis,Persistence to treatment,Italy

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