DYRK Kinase Pom1 Drives F-BAR Protein Cdc15 from the Membrane to Promote Medial Division.

Rahul Bhattacharjee,MariaSanta C. Mangione, Marcin Wos,Jun-Song Chen,Chloe E. Snider,Rachel H. Roberts-Galbraith,Nathan A. McDonald,Libera Lo Presti,Sophie G. Martin,Kathleen L. Gould

Molecular biology of the cell（2020）

Cited 18|Views15

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Abstract

Phosphorylation by the DYRK kinase Pom1 is one of two major signals for proper division site placement in Schizosaccharomyces pombe. Pom1 phosphorylation of F-BAR protein Cdc15 inhibits its membrane and protein binding, thus inhibiting scaffolding of the cytokinetic ring and preventing mislocalized division.

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