Phosphatidylcholine solubility in supercritical carbon dioxide: Experimental data, thermodynamic modeling, and application in bioactive-encapsulated liposome synthesis

•Solubility of phosphatidylcholine in supercritical CO2 was measured.•The solubility data was accurately modeled using three cubic equations of state.•The best solubility state was used to synthesize liposome for bioactive delivery.•Liposomes encapsulation yield was 95, 77, 63 % for vitamin-E, vitamin-C, and iron.