P420 Understanding PrEP service delivery preferences among black women in urban and rural counties in the US deep south

Background In the US, women account for approximately 20% of all new HIV infections, among which two-thirds are Black women. These health disparities are most pronounced in the Deep South. We conducted focus groups in urban and rural settings in Alabama to understand attitudes and preferences for PrEP service delivery among Black women. Methods Our group members consisted of HIV-negative women between the ages of 16–65. Items and analyses were grounded in a conceptual framework using constructs from two behavioral models. Two coders independently conducted inductive and deductive thematic coding to determine major themes. Results 25 rural (median age 44, 48% income Conclusion Black women in the Deep South had differing preferences regarding PrEP service delivery and messaging depending on whether they lived in urban or rural settings. These findings can inform targeted intervention development by emphasizing the need for partnerships with trusted community organizations and utilization of service delivery strategies that allow for anonymity to increase uptake of PrEP especially among rural Black women. Disclosure No significant relationships.