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Role of the Calcified Cartilage Layer of an Integrated Tri-layered Silk Fibroin Scaffold Used to Regenerate Osteochondral Defects in Rabbit Knees

ACS Biomaterials Science & Engineering, no. 2 (2020): 1208-1216

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The repair of osteochondral defects (OCDs) remains challenging given the complexity of native osteochondral tissue and the limited self-repair capacity of cartilage. Osteochondral tissue engineering is a promising strategy. Here, we fabricated a biomimetic osteochondral scaffold using silk fibroin (SF) and hydroxyapatite (HA) including a ...更多

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作者
Yanhong Zhao
Yanhong Zhao
Xiaoming Ding
Xiaoming Ding
Yunsheng Dong
Yunsheng Dong
Xun Sun
Xun Sun
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