P1740 Normal values for TAPSE in the HUNT study of subjects without evidence of heart disease

Abstract Background TAPSE is a simple and robust measure of RV function, but only in the absence of regional dysfunction and translational effects from the LV. Normal values from large normal studies are scarce, however. The aim of this study was to present normal values from the HUNT 3 study. Methods The HUNT study examined 1266 subjects without evidence of heart disease, from a mixed urban / rural population of North Tøndelag county in Norway. TAPSE was measured by reconstructed M-mode through the lateral tricuspid ring of the RV, in apical four-chamber view as shown in figure 1. Results Age and gender related values are given in table 1. TAPSE was normally distributes with a skewness of 0.42. Mean TAPSE was 2.8 cm (SD = 0.5), TAPSE declined with increasing age (p < 0.001), but the correlation with age was moderate (R=-0.15, p < 0.001). There was only a small gender difference (p < 0.001), and a moderate correlation with BSA (R = 0.24, p < 0.005). In linear regression with BSA and gender, only BSA was significant. Conclusions As all long axis measures, it declines with age, but this is moderate, so the relevance of age-specific measures can be discussed. TAPSE is near gender independent, and gender differences are only due to body size. Age and gender related values for TAPSE Age (years): <40 40-60 >60 All Women TAPSE(cm) 2.9 (0.5) 2.7 (0.5) 2.5 (0.5) 2.8 (0.5) Men TAPSE(cm) 3.0 (0.6) 2.9 (0.6) 2.8 (0.6) 2.9 (0.6) All TAPSE(cm) 2.9 (0.5) 2.8 (0.5) 2.7 (0.5) 2.8 (0.5) Abstract P1740 Figure. Fig. 1