Study on the expression and function of smad family member 7 in oral submucous fibrosis and oral squamous cell carcinoma.

Xin Hu,Haofeng Xiong,Weiming Wang,Long Huang,Ting Mao,Liudi Yang,Can Wang,Danni Huang,Jin Wu,Kun Xia,Tong Su

Archives of Oral Biology（2020）

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摘要

•Smad family member 7 (SMAD7) is a promoter of oral submucous fibrosis (OSF).•SMAD7 is a promoter of oral squamous cell carcinoma (OSCC).•The up-trends of SMAD7 expression were consistent in OSF and OSCC.•Bioinformatics online analyses were used to indicate the functions of SMAD7.•Study on the expression and function of smad family member 7 in oral submucous fibrosis and oral squamous cell carcinoma.

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关键词

SMAD7,OSF,OSCC,TGF-β,NOM,AD,TCGA,HNSC,GO,KEGG,SEM

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