RNAi Nanotherapy for Fibrosis: Highly Durable Knockdown of CTGF/CCN-2 Using Sirna-Degradaball (LEM-S401) to Treat Skin Fibrotic Diseases.

Seounghun Kang,Jun Kim,Minchul Ahn,Jungho Kim,Myeong-Gang Heo,Dal-Hee Min,Cheolhee Won

Nanoscale（2020）

引用 14|浏览12

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摘要

LEM-S401, siRNA against CTGF with DegradaBALL, could be a highly potent RNAi therapeutics for skin fibrotic diseases by inducing long lasting knockdown of CTGF with lower dosage and fewer injections.

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