Circulating levels of soluble urokinase plasminogen activator receptor predict outcome after resection of biliary tract cancer.

•Biliary tract cancer is associated with poor outcomes and increasing incidence.•Surgical resection is the only potentially curative treatment option for patients with biliary tract cancer.•The identification of ideal surgical candidates has remained challenging.•Circulating suPAR represents a novel diagnostic and prognostic biomarker in resectable patients.•SuPAR might be useful to identify patients with biliary tract cancer who will benefit most from tumor resection.