Advanced glycation end products inhibit neural stem cell differentiation via upregualtion of HDAC3 expression.

Yi Bao,Haiyan Chen,Zheng Cai,Jiaoyang Zheng,Junjie Zou,Yongquan Shi,Lei Jiang

Brain Research Bulletin（2020）

引用 6|浏览15

暂无评分

摘要

•Advanced glycation end products interfered with normal differentiation of neural stem cells.•Histone deacetylase 3 (HDAC3) was increased in neural stem cells of diabetic mice.•Knocking down the expression of HDAC3 could partially attenuate the inhibitory effect of AGEs on NSC differentiation.

查看译文

关键词

Diabetes mellitus,Neural stem cell,Advanced glycation end products,HDAC3

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要