Trametinib response in heavily pretreated high-grade ovarian cancer: one step towards precision medicine

Gynecologic Oncology Reports(2020)

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摘要
•New therapies are needed for advanced or recurrent high-grade ovarian cancer.•Genetic and molecular tests may help in directing therapeutic options according to sensitivity profiles.•Trametinib showed promising response in our patient affected by heavily pretreated high-grade ovarian cancer.
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关键词
Ovarian neoplasm,Ovarian epithelial cancer,Genetic testing,Precision medicine,Target therapy,Trametinib
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