Adenosine Receptor Blockade With Ciforadenant Plus /- Atezolizumab In Advanced Metastatic Castration-Resistant Prostate Cancer (Mcrpc)

Lauren Christine Harshman,Michael Chu,Saby George,Brett Gordon Maxwell Hughes,Bradley Curtis Carthon,Lawrence Fong,Jaime R. Merchan,Long Kwei,Andrew N. Hotson,Mehrdad Mobasher,Richard A. Miller

JOURNAL OF CLINICAL ONCOLOGY（2020）

引用 23|浏览63

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摘要

129Background: Adenosine, generated by the ectonucleotidase CD73, mediates immunosuppression within the tumor microenvironment by triggering adenosine 2A receptors (A2AR) on immune cells. Tumor CD7...

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关键词

prostate cancer,mcrpc,castration-resistant

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