Contribution Of Extragonadal Steroids To The Androgen Receptor Activity And To The Castration-Resistance Development In Recurrent Prostate Cancers After Primary Therapy

Frederic Pouliot,Mélanie Rouleau,Bertrand Neveu,Paul Toren,Fannie Morin,Lauriane Vélot,Keyue Ding,Patrick Caron,Louis Lacombe,Eric Levesque,Laurence Klotz,Chantal Guillemette

JOURNAL OF CLINICAL ONCOLOGY（2020）

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摘要

148Background: Beyond testosterone, several steroids contribute to the activation of the androgen receptor (AR) pathway, but their relative contributions in castrated prostate cancer (PCa) patients...

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关键词

androgen receptor activity,recurrent prostate cancers,extragonadal steroids,castration-resistance

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