A Phase I Study To Evaluate Psca-Targeting Chimeric Antigen Receptor (Car)-T Cells For Patients With Psca Plus Metastatic Castration-Resistant Prostate Cancer (Mcrpc)

Tanya B. Dorff,Suzette Blanchard, Patti Carruth,Jamie Wagner,Peter Kuhn,Ammar Chaudhry,Lauren Adkins,Sandra Thomas,Hripsime Martirosyan,Peiguo Chu,Sumanta K. Pal,Stephen J. Forman,Saul Priceman

JOURNAL OF CLINICAL ONCOLOGY（2020）

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摘要

TPS250Background: Although treatment options have improved, mCRPC remains highly lethal. Immunotherapy holds potential for durable remissions but not yet in mCRPC. CAR-T cell therapy has yielded cu...

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关键词

chimeric antigen receptor,mcrpc,prostate,psca-targeting,castration-resistant

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