Mechanistic Characterization of the Fusicoccane-type Diterpene Synthase for Myrothec-15(17)-en-7-ol

Fu-Long Lin,Lukas Lauterbach,Jian Zou,Yong-Heng Wang,Jian-Ming Lv,Guo-Dong Chen,Dan Hu,Hao Gao,Xin-Sheng Yao,Jeroen S. Dickschat

ACS Catalysis（2020）

引用 18|浏览23

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摘要

Fusicoccane (FC)-type diterpenes, featuring a common 5–8–5 tricyclic skeleton, possess diverse biological functions. Currently, only FC-type diterpene synthases (DTSs) for 3 of the 16 possible ster...

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关键词

terpenoids,biosynthesis,enzyme mechanisms,isotopes,DFT calculations

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