Bone Mineral Density and Progression Rate of Calcific Aortic Valve Stenosis

Lionel Tastet,Mylène Shen,Romain Capoulade,Marie Arsenault,Élisabeth Bédard,Nancy Côté,Marie-Annick Clavel,Philippe Pibarot

Journal of the American College of Cardiology（2020）

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摘要

Calcific aortic valve stenosis (AS) is the most prevalent heart valve disease in high-income countries ([1][1]). There is currently no effective pharmacotherapy to prevent or reduce its progression. The pathobiology of AS is complex and involves several mineralizing processes, similar to skeletal

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