Identification of the miRNA-3185/CYP4A11 axis in cardiac tissue as a biomarker for mechanical asphyxia.

Liujun Han,Heng Zhang,Yan Zeng,Yehui Lv,Li Tao,Jianlong Ma,Hongmei Xu,Kaijun Ma,Qun Shi,Bi Xiao,Long Chen

Forensic Science International（2020）

引用 11|浏览28

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摘要

•miR-3185 is specifically up-regulated in the cardiac tissue of mechanical asphyxia.•No correlation between the expression of miR-3185 and postmortem interval, age or temperature.•miR-3185 regulates the down regulation of CYP4A11 in the death process of mechanical asphyxia.

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关键词

Mechanical asphyxia,Biomarker,MiRNA-3185,CYP4A11,Cardiac tissue

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