Single-cell transcriptional networks in differentiating preadipocytes suggest drivers associated with tissue heterogeneity

Alfred K Ramirez
Alfred K Ramirez
Bashir Rastegarpanah
Bashir Rastegarpanah
Ruidan Xue
Ruidan Xue

NATURE COMMUNICATIONS, pp. 21172020.

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Abstract:

White adipose tissue plays an important role in physiological homeostasis and metabolic disease. Different fat depots have distinct metabolic and inflammatory profiles and are differentially associated with disease risk. It is unclear whether these differences are intrinsic to the pre-differentiated stage. Using single-cell RNA sequencing...More

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