Changes in redox state of albumin before and after kidney transplantation in patients with end-stage renal disease.

Ryota Tanaka,Tadashi Imafuku,Yosuke Suzuki,Kento Nishida,Kotaro Matsusaka,Toshitaka Shin,Yuhki Sato,Yu Ishima,Hiroshi Watanabe,Hiromitsu Mimata,Toru Maruyama,Hiroki Itoh

Clinical Biochemistry（2020）

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摘要

•ESI-TOFMS method identified three HSA isoforms cysteinylated at the Cys34 residue.•ESI-TOFMS method identified three HSA isoforms without Cys34 cysteinylation.•Reduced HSA concentration did not change until day 14 after kidney transplantation.•Reduced HSA levels increased at day 30 and remained stably elevated until day 180.

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关键词

Albumin,Post-translational modification,Kidney transplantation,Cysteinylation,Oxidative stress

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