Combined G-CSF and Plerixafor enhance hematopoietic recovery of CD34 + cells from poor mobilizer patients in NSG mice.

M L Arcangeli,P Brault, J H Bourhis, F Kuhnowski, E Henry, V Barroca,S Koscielny,F Pflumio,S Amsellem

Experimental Hematology（2020）

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摘要

•G-CSF + Plerixafor increases mobilized-HSC quality, in case of poor mobilizer patients.•G-CSF + Plerixafor-mobilized CD34+ cells have a high in vivo hematopoietic potential.•G-CSF + Plerixafor induces the mobilization of HSC with high engraftment capacity.

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