Nutrition and the ageing brain: Moving towards clinical applications

Emma Flanagan, Daniel Lamport,Lorraine Brennan,Philip Burnet,Vittorio Calabrese,Stephen C. Cunnane,Martijn C. de Wilde,Louise Dye,Jonathan A. Farrimond, Nancy Emerson Lombardo,Tobias Hartmann,Thomas Hartung,Marko Kalliomäki, Gunther G. Kuhnle,Giorgio La Fata,Aleix Sala-Vila,Cécilia Samieri,A. David Smith,Jeremy P.E. Spencer,Sandrine Thuret

Ageing Research Reviews（2020）

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摘要

•Diet is a promising approach for the prevention of age-related neurodegeneration.•Focus has shifted from individual nutrients to whole diets for improving brain health.•Shift in microbiome diversity may affect brain ageing.•Dietary manipulation of the gut microbiota may improve brain functions in ageing.•Brain imaging, modelling and new biomarkers are improving diet and ageing research.

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关键词

Brain,Healthy ageing,Preventative diet,Microbiota,Neuroprotection,Cognitive ageing

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