Prognostic gene expression signature for high-grade serous ovarian cancer
Annals of Oncology(2020)
摘要
•A gene expression signature for high-grade serous ovarian cancer prognostic for 2- and 5-year overall survival (OS).•The 101 gene expression signature performs substantially better than age and stage alone.•Median survival by quintile was 9.5, 5.4, 3.8, 3.2 and 2.3 years.•The top five genes associated with OS were TAP1, ZFHX4, CXCL9, FBN1, and PTGER3 (P < 0.001).
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关键词
formalin-fixed paraffin-embedded,gene expression,high-grade serous ovarian cancer,overall survival,prognosis
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