Lin28A promotes IRF6-regulated aerobic glycolysis in glioma cells by stabilizing SNHG14

Jinjing Lu
Jinjing Lu
Jian Zheng
Jian Zheng
Jian Song
Jian Song
Xuelei Ruan
Xuelei Ruan
Shuyuan Shen
Shuyuan Shen
Lianqi Shao
Lianqi Shao
Chunqing Yang
Chunqing Yang
Di Wang
Di Wang
Shuo Cao
Shuo Cao

CELL DEATH & DISEASE, pp. 4472020.

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Abstract:

Warburg effect is a hallmark of cancer cells, wherein glycolysis is preferred over oxidative phosphorylation even in aerobic conditions. Reprogramming of glycometabolism is especially crucial for malignancy in glioma. RNA-binding proteins and long noncoding RNAs are important for aerobic glycolysis during malignant transformation. Thus, w...More

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