MicroRNA-4331-5p promotes FMDV replication through inhibiting interferon pathways in PK-15 cells.

Tingting Ren,Yanxue Wang,Haotai Chen,Kailing Wang, Xin Gao,Lei Liu,Yongguang Zhang,Yuefeng Sun

Virus Research（2020）

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摘要

•FMDV infection up-regulates miRNA-4331-5p expression.•MiRNA-4331-5p mimics transfection facilitates FMDV replication.•MiRNA-4331-5p inhibitor transfection suppresses FMDV replication.•MiRNA-4331-5p regulates interferon production and antiviral genes expression during FMDV infection.

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关键词

miRNAs,FMDV,Interferon

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