Anti-inflammatory potential of Patrineolignan B isolated from Patrinia scabra in LPS-stimulated macrophages via inhibition of NF-κB, AP-1, and JAK/STAT pathways.

Hwi-Ho Lee,Eungyeong Jang,Shin-Young Kang,Ji-Sun Shin,Hee-Soo Han,Tae-Woo Kim,Da Hye Lee,Jang-Hoon Lee,Dae Sik Jang,Kyung-Tae Lee

International Immunopharmacology（2020）

引用 27|浏览28

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摘要

•Patrineolignan B (PB) exhibits anti-inflammatory potency through interfering with the NF-κB, AP-1, and JAK/STAT signaling pathway in LPS-stimulated macrophages.•Patrineolignan B (PB) shows potential as an active compound against inflammation-related diseases.

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关键词

Patrineolignan B,Inflammation,NF-κB,AP-1,JAK/STAT,RAW 264.7 macrophages

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