NCBP3/SNHG6 inhibits GBX2 transcription in a histone modification manner to facilitate the malignant biological behavior of glioma cells

Xiwen Li
Xiwen Li
Fangfang Zhang
Fangfang Zhang
Xuelei Ruan
Xuelei Ruan
Jian Zheng
Jian Zheng
Shuo Cao
Shuo Cao
Shuyuan Shen
Shuyuan Shen
Lianqi Shao
Lianqi Shao

RNA biology, 2020.

Cited by: 0|Views19
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Abstract:

RNA-binding proteins (RBPs) are significantly dysregulated in glioma. In this study, we demonstrated the upregulation of Nuclear cap binding subunit 3 (NCBP3) in glioma tissues and cells. Further, knockdown of NCBP3 inhibited the malignant progression of glioma. NCBP3 directly bound to small nucleolar RNA host gene 6 (SNHG6) and stabilize...More

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