Continuous in-line homogenization process for scale-up production of naltrexone-loaded PLGA microparticles

Farrokh Sharifi
Farrokh Sharifi
Gwangheum Yoon
Gwangheum Yoon

Journal of Controlled Release, pp. 347-358, 2020.

Cited by: 0|Views2
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Abstract:

Injectable, long-acting drug delivery systems provide effective drug concentrations in the blood for up to 6 months. Naltrexone-loaded poly(lactide-co-glycolide) (PLGA) microparticles were prepared using an in-line homogenization method. It allows the transition from a laboratory scale to scale-up production. This research was designed to...More

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