Effects of Y1 receptor agonist on the pancreatic islet of diet-induced obese and diabetic mice

Priscila Viana Carapeto,Carlos A Mandarim-de-Lacerda,Marcia Barbosa Aguila

Journal of Diabetes and its Complications（2020）

引用 2|浏览11

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摘要

•The failure of the action of NPY leads to hyperglycemia and hyperinsulinemia.•We studied Y1 activation in a model of obesity and insulin resistance.•Y1 agonist activates PDX1/STAT3 pathway regulating insulin release by beta-cell.

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关键词

Neuropeptide Y,Y1 agonist,Beta-cell,Diabetes,Obesity

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