Treatment of chronic hepatitis B na ï ve patients with a therapeutic vaccine containing HBs and HBc antigens ( a randomized , open and treatment controlled phase III clinical trial )

1 Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh, 2 Department of Medical Sciences, Toshiba General Hospital, Tokyo, Japan, 3 Department of Biomedical Research, Center for Genetic Engineering and Biotechnology, Havana, Cuba, 4 Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime, Japan, 5 Department of Medicine, Sai Sei Kai Imabari Hospital, Imabari, Japan