Relative roles of GM 1 ganglioside , N-acylneuraminic acids and α 2 β 1 integrin in 1 mediating rotavirus infection 2 3

Relative roles of GM1 ganglioside, N-acylneuraminic acids and α2β1 integrin in 1 mediating rotavirus infection 2 3 Fiona E. Fleming, Raphael Böhm , Vi T. Dang , Gavan Holloway, Thomas 4 Haselhorst, Paul D. Madge, Jaigeeth Deveryshetty, Xing Yu, Helen Blanchard, Mark 5 von Itzstein and Barbara S. Coulson 6 7 Department of Microbiology and Immunology, Peter Doherty Institute for Infection and 8 Immunity at The University of Melbourne, Melbourne, Victoria 3010, Australia 9 Institute for Glycomics, Griffith University, Gold Coast Campus, Queensland 4222, 10 Australia 11 These authors contributed equally to this work. 12 13 Corresponding author: Barbara S. Coulson, Department of Microbiology and 14 Immunology, Gate 11, Royal Parade, The University of Melbourne, Parkville, Victoria 15 3010, Australia. Tel: +61 3 8344 8823, Fax: +61 3 9347 1540, Email: 16 barbarac@unimelb.edu.au 17 18 Running title: GM1, sialic acid and integrin as rotavirus receptors 19 Word counts: Abstract 250, Text 6456 20 21 22 JVI Accepts, published online ahead of print on 5 February 2014 J. Virol. doi:10.1128/JVI.03431-13 Copyright © 2014, American Society for Microbiology. All Rights Reserved.