Lens Wnt 5 a Contributes to the Differentiation of Human Embryonic Stem Cells into Lentoid Bodies Through the Noncanonical Wnt / JNK Signaling Pathway

Citation: Han C, Li J, Wang C, et al. Wnt5a contributes to the differentiation of human embryonic stem cells into lentoid bodies through the noncanonical Wnt/JNK signaling pathway. Invest Ophthalmol Vis Sci. 2018;59:3449–3460. https://doi.org/ 10.1167/iovs.18-23902 PURPOSE. Recent work has indicated that Wnt5a has a critical role in embryonic development. We investigate whether the Wnt5a-activated noncanonical Wnt pathway is capable of promoting embryonic lens differentiation.