MiR-200 c suppresses TGF-b signaling and counteracts trastuzumab resistance and metastasis by targeting ZNF 217 and ZEB 1 in breast cancer

Wen-Dong Bai, Xing-Ming Ye, Meng-Yao Zhang, Hua-Yu Zhu, Wen-Jin Xi, Xun Huang, Jiao Zhao, Bin Gu, Guo-Xu Zheng, An-Gang Yang and Lin-Tao Jia 1 State Key Laboratory of Cancer Biology, Department of Immunology, Fourth Military Medical University, Xi’an, Shaanxi, China 2 Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi’an, Shaanxi, China 3 Cell Engineering Research Center, Department of Cell Biology, Fourth Military Medical University, Xi’an, Shaanxi, China 4 School of Graduate Studies, Fourth Military Medical University, Xi’an, Shaanxi, China