FDG PET / CT Early Dynamic Blood Flow and Late Standardized Uptake Value Determination in Hepatocellular Carcinoma 1

Hanna Bernstine , MD Marius Braun , MD Nikolay Yefremov , MD Yechiel Lamash , MSc Raz Carmi , PhD Dorit Stern , MD Adam Steinmetz , MD Jacob Sosna , MD David Groshar , MD Purpose: To prospectively determine whether fl uorine 18 fl uorodeoxyglucose (FDG) positron emission tomography (PET)/ computed tomography (CT) early dynamic blood fl ow estimates could be used to discriminate hepatocellular carcinoma (HCC) from background liver and to characterize HCC in patients with and those without angioinvasion; and to evaluate the association between blood fl ow measures at FDG PET/CT with metabolism in HCCs.