Impact of Toxoplasma ROPs/GRAs on Host Transcription Differential Impacts on Host Transcription by ROP and GRA Effectors from the 1 Intracellular Parasite Toxoplasma gondii

Differential Impacts on Host Transcription by ROP and GRA Effectors from the 1 Intracellular Parasite Toxoplasma gondii 2 Suchita Rastogi, Yuan Xue, Stephen R. Quake*, John C. Boothroyd* 3 *Equal contribution 4 5 Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, 6 CA, USA 7 Department of Bioengineering, Stanford University, Stanford, CA, USA 8 Department of Applied Physics, Stanford University, Stanford, CA, USA 9 Chan Zuckerberg Biohub, San Francisco, CA, USA 10 11 Correspondence should be addressed to J.C.B. (jboothr@stanford.edu) and S.R.Q. 12 (steve@quake-lab.org). 13 14 15 Abstract: 220 words 16