P6: fish allergy among 88 fish‐allergic children and the allergenicity of 66 fish species

Introduction: The fish nematode Anisakis spp. whose larvae occupy several types of fish and cephalopods and is a known cause of gastrointestinal infection after ingestion of seafood. IgE sensitisation to Anisakis spp. can cause urticaria, angioedema and anaphylaxis. Specific IgE testing and skin tests are used to make the diagnosis of Anisakis spp. allergy by detecting specific IgE to Anisakis spp. in the absence of IgE to the consumed seafood. Whole body antigen extracts form Anisakis spp. are used in these assays but can cause false positive results due to homology between Anisakis spp. allergens and proteins in other nematodes, shellfish or insects. The purpose of this study was to determine how common a positive serology specific IgE to Anisakis spp. in Australia was and to assess the positive results with other seafood allergens.