DEPTOR is a microRNA-155 target regulating migration and cytokine production in diffuse large B-cell lymphoma cells

Ewa Jabłońska,Emilia Białopiotrowicz,Maciej Szydłowski,Monika Prochorec-Sobieszek,Przemysław Juszczyński,Anna Szumera-Ciećkiewicz

Experimental Hematology（2020）

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摘要

•MiR-155 represses expression of DEPTOR and c-CBL in DLBCL cells.•DEPTOR expression is decreased in non-GCB DLBCLs.•DEPTOR favors the migration of DLBCL cells and suppresses the expression of pro-inflammatory cytokines in DLBCL cells.

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关键词

AKT,BCR,DEPTOR,DLBCL,NFĸB,c-CBL,miR-155,microRNA

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