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Oxidative Trimerization of Indoles Via Water-Assisted Visible-Light Photoredox Catalysis and the Study of Their Anti-Cancer Activities.

Organic & biomolecular chemistry(2020)

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摘要
Incorporation of water has been revealed to successfully facilitate visible-light photoredox catalysis of indole leading to increased production of C2-quaternary indolinone. The water-promoted photoreaction of indole under catalyst-free conditions by a household compact fluorescence light was also demonstrated. The antiproliferative activity of the synthesized indolinones was evaluated against three human cancer cell lines.
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