Effects of Febuxostat on Mortality and Cardiovascular Outcomes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Ahmad Al-Abdouh,Safi U Khan,Mahmoud Barbarawi,Sireesha Upadhrasta, Srajum Munira,Anas Bizanti,Hadi Elias, Asadulla Jat,Di Zhao,Erin D Michos

Mayo Clinic Proceedings: Innovations, Quality & Outcomes（2020）

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摘要

This meta-analysis suggested that use of febuxostat was not associated with higher risk of mortality or adverse cardiovascular outcomes in patients with gout and hyperuricemia. The results were limited by low to moderate certainty of evidence.

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关键词

CARES trial,CVD,MACE,MI,RCT,RD

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