Ligation of random oligomers leads to emergence of autocatalytic sequence network

Cited by: 0|Bibtex|Views2|DOI:https://doi.org/10.1101/2020.08.18.253963
Other Links: arxiv.org

Abstract:

The emergence of longer information-carrying and functional nucleotide polymers from random short strands was a major stepping stone at the dawn of life. But the formation of those polymers under temperature oscillation required some form of selection. A plausible mechanism is template-based ligation where theoretical work already sugge...More

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