Impact of Treatment Intensification According to Patient Prognosis: A Pooled Analysis of 3 Randomized Phase III Trials

Mattia D'Agostino,Andrew Spencer,Pellegrino Musto,Sara Bringhen,Emanuele Angelucci,Fabio Ciceri,Lucio Catalano,Marco Salvini,Anna Baraldi,Sonia Grandi,Alessandro Rambaldi,Alberto Bosi,Iolanda Donatella Vincelli,Paola Omede,Mariella Grasso,Roberto Marasca,Maria Cantonetti,Annalisa Bernardini,Nicola Cascavilla,Francesca Patriarca, Rossella Troia, Roberto Ria, Anna Marina Liberati, Alessandra Larocca, Tommaso Caravita di Toritto, Roman Hajek, Antonio Palumbo, Mario Boccadoro, Francesca Gay

Clinical lymphoma myeloma & leukemia/Clinical lymphoma, myeloma and leukemia（2017）

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摘要

Curable hematologic tumors but not multiple myeloma (MM) benefit from risk-adapted therapy. Intensified treatments such as autologous stem cell transplantation (ASCT) and continuous therapy (CT) improve patients (pts) outcome. A better evaluation of pts prognosis based on the revised international staging system (R-ISS) is now available. We evaluated the impact of ASCT and CT in pts with different baseline prognosis.

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