Liver fibrosis score, physical frailty, and the risk of dementia in older adults: The Italian Longitudinal Study on Aging.

Vincenzo Solfrizzi,Emanuele Scafato,Carlo Custodero,Francesca Loparco,Alessandro Ciavarella,Francesco Panza,Davide Seripa,Bruno Pietro Imbimbo,Madia Lozupone,Nicola Napoli,Giuseppina Piazzolla,Lucia Galluzzo,Claudia Gandin,Marzia Baldereschi,Antonio Di Carlo,Domenico Inzitari,Alberto Pilotto,Carlo Sabbà

Alzheimer's & dementia (New York, N. Y.)（2020）

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摘要

Advanced liver fibrosis (F3-F4 NFS) could be a long-term predictor for overall dementia in people with physical frailty. These findings should encourage a typical geriatric, multidisciplinary assessment which accounts also for the possible co-presence of frail condition in older adults with chronic liver disease and liver fibrosis.

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关键词

NAFLD fibrosis score,dementia,frailty,older adults,population‐based study

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