Estimation of p70S6K Thr(389) and 4E-BP1 Thr(37/46) phosphorylation support dependency of tension per se in a dose-response relationship for downstream mTORC1 signalling

In a letter to the editor by Figureiredo et al , entitled "On the appropriateness of antibody selection to estimate mTORC1 activity", the authors question our choice of mTORC1 biomarkers . We much appreciate the input and the possibility to emphasize our conclusions.